2016-2020

2020

1. Wong J. H., Bao H., Ng T. B., Chan H. H. L., Ng C. C. W., Man G. C. W., Hexiang W., Guan S., Zhao S., Fang E. F., Rolka K., Liu Q., Li Q., Sha O., Xia L., New ribosome inactivating proteins and other proteins with protein synthesis inhibiting activities, Appl. Microbiol. Biot., 104, 4211-4226 (2020); DOI: 10.1007/s00253-020-10457-7 .

2. Wong J. H., Ng T. B., Chan H. H. L., Liu Q., Man G. C. W., Zhang C. Z., Guan S., Ng C. C. W., Fang E. F., Wang H., Liu F., Ye X., Rolka K., Naude R., Zhao S., Sha O., Li C., Xia L., Mushroom extracts and compounds with suppressive action on breast cancer:Evidence from studies using cultured cancer cells, tumor bearing animals and clinical trials, Appl. Microbiol. Biot., 104, 4675-4703 (2020); DOI:10.1007/s00253-020-10476-4

3. Gitlin-Domagalska A., Dębowski D., Gucwa K., Starego D., Ptaszyńska N., Sieradzan A., Karczyńska A., A.Samsonow S., Mangold M.,  Gütschow M., Łęgowska A., RolkaK., Truncation of Huia versabilis Bowman-Birk inhibitor increases its selectivity, matriptase-1 inhibitory activity and proteolytic stability, Biochimie, 171–172, 178-186 (2020), DOI: 10.1016/j.biochi.2020.03.006

4. Ptaszyńska N. Gucwa K., Olkiewicz K., Heldt M., Serocki M., Stupak A., Martynow D., Dębowski D., Gitlin-Domagalska A., Lica J., Łęgowska A., Milewski S., Rolka R., Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity, Int. J. Mol. Sci., 21, 4696, (2020); doi:10.3390/ijms21134696

5. LesiówM., Bieńko A., Sobańska K., Kowalik-Jankowska T., Rolka K., Łęgowska A., Ptaszyńska N., Cu(II) complexes with peptides from FomA protein containing -His-Xaa-YaaZaa-His and -His-His-motifs. ROS generation and DNA degradation, I. Inorg. Biochem., 212, 111250 (2020); doi: 10.1016/j.jinorgbio.2020.111250;

6. Lesiów M.K., Pietrzyk P., Bieńko A., Kowalik-Jankowska T., Łęgowska A., Ptaszyńska N., Rolka K., Correction: Stability of Cu(II) complexes with FomA protein fragments containing two His residues in the peptide chain, Metallomics, 12, 2199 (2020); DOI: 10.1039/d0mt90038a;

7. Gilon C., Gitlin-Domagalska A., Lahiani A., Yehoshua- Alshanski S., Shumacher-Klinger A., Gilon D., Taha M., Sekler I., Hoffman A., Lazarovici P.*, Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults, Peptides, 2020, 134, 170399, DOI: 10.1016/j.peptides.2020.170399

8. Gitlin-Domagalska A., Maciejewska A., Dębowski D.*, Bowman-Birk inhibitors: insights into family of multifunctional proteins and peptides with potential therapeutical applications, Pharmaceuticals, 2020, 13(12), DOI: 10.3390/ph13120421

2019

1. Ptaszyńska N., Olkiewicz K., Okońska J., Gucwa K., Łęgowska A., Gitlin-Domagalska A., Debowski D., Lica J., Heldt M., Milewski S., Ng T.B., Rolka K., Peptide Conjugates Of Lactoferricin Analogues And Antimicrobials - Design, Chemical Synthesis, And Evaluation Of Antimicrobial Activity And Mammalian Cytotoxicity, Peptides. 2019 Apr 5. pii: S0196-9781(19)30037-3. doi: 10.1016/j.peptides.2019.04.006.

2. Ptaszyńska N., Gucwa K., Olkiewicz K., Łȩgowska A., Okońska J., Ruczyński J., Gitlin-Domagalska A., Dȩbowski D., Milewski S., Rolka K., Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities, ACS Chem Biol. 14, 2233-2242 (2019). doi: 10.1021/acschembio.9b00538.

3. Lesiów M. K., Pietrzyk P., Rolka K., Kyzioł A., Komarnicka U. K., Correction: Cu(II) Complexes with FomA Protein Fragments of Fusobacterium Nucleatum Increase Oxidative Stress and Malondialdehyde Level (Chem. Res. Toxicol.(2019)32: 11(2227-2237)Doi: 10.1021/acs.chemrestox.9b00269), Chem. Res. Toxicol., 33, 2218-2218 (2020); DOI: 10.1021/acs.chemrestox.0c00282

4. Naoum J., Alshanski I., Gitlin-Domagalska A., Bentolila M., Gilon C., Hurevich M.*, Diffusion Enhanced Amide Bond Formation on Solid Support, Org. Process Res. Dev., 2019, 23, 12, 2733-2739, DOI: 10.1021/acs.oprd.9b00398

2018

1. Lesiów M.K., Komarnicka U.K., Stokowa-Sołtys K., Rolka K., Łęgowska A., Ptaszyńska P., Wieczorek A., Kyzioł A., Jeżowska-Bojczuka M., Relationship between copper(II) complexes with FomA adhesin fragments of F. nucleatum and colorectal cancer. Coordination pattern and ability to promote ROS production, Dalton Trans., 47, 5445-5458 (2018).

2. Cheung R. C. F.F., Ng T. B., Wong J. H., Naude R., Rolka K., Tse T.F., Chan H., Tse R., Sze S. C. W., Tuber lectins with potentially exploitable bioactivities, Curr. Med. Chem., 25, (2018).

3. Ptaszyńska N., Gucwa K., Łęgowska A., Dębowski D., Gitlin-Domagalska A., Lica J., Heldt M., Martynow D., Olszewski M., Milewski S., Ng T.B., Rolka K., Antimicrobial Activity of Chimera Peptides Composed of Human Neutrophil Peptide 1 (HNP-1) Truncated Analogues and Bovine Lactoferrampin, Bioconjugate Chem., 29, 3060-3071 (2018).

4. Lubos M., Dębowski D., Bracińska E., Inkielewicz-Stępniak I., ², Annika M., Burster T., Rolka K., Inhibition of human constitutive 20S proteasome and 20S immunoproteasome with novel N-terminally modified peptide aldehydes and their anti-tumor activity, Biopolymers, 2018, doi: 10.1002/pep2.24100

5. Krupa K., Lesiówa M., Stokowa-Sołtysa K., Starosta R., Ptaszyńska N., Łęgowska A., Rolka K. Wernecki M., Cal M., Jeżowska-Bojczuk M., Copper(II) complexes with Fusobacterium nucleatum adhesin FadA:Coordination pattern, physicochemical properties and reactivity J. Inorg. Chem. 189, 69-80 (2018).

6. Schumacher-Klinger A., Fanous J., Merzbach S., Weinmüller M., Reichart F., Räder A.F.B., Gitlin-Domagalska A., Gilon C., Kessler H., Hoffman A., Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway, Mol. Pharm., 2018, 15, 3468-3477.

7. Alshanski I., Bentolila M., Gitlin-Domagalska A., Zamir D., Zorsky S., Joubran S., Hurevich M., Gilon C., Enhancing the Efficiency of the Solid Phase Peptide Synthesis (SPPS) Process by High Shear Mixing, Org. Process Res. Dev., 2018, 22, 1318–1322.

8. Gitlin-Domagalska A., Mangold M., Dębowski D.,Ptaszyńska N., Łęgowska A., Gütschow M., Rolka K., Matriptase-2: Monitoring and Inhibiting its Proteolytic Activity, Future Med. Chem., w druku

2017

1. Gitlin-Domagalska A., Dębowski D., Łęgowska A., Stirnberg M., Okońska J., Gütschow M., Rolka K., Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds, Biopolymers, 2017 May 27. doi: 10.1002/bip.23031.

2. Filipowicz M., Ptaszyńska N., Olkiewicz K., Dębowski D., Ćwikłowska K., Burster T., Pikuła M., Krzystyniak A., Łęgowska A., Rolka K., Spliced analogues of trypsin inhibitor SFTI-1 and their application for tracing proteolysis and delivery of cargos inside the cells, Biopolymers, 108(2) (2017)

2016

1. Gruba N., Wysocka M., Brzezińska M., Debowski D., Rolka K., Martin N., Lesner A., Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome, Anal Biochem.,508,38-45 (2016).

2. Gruba N., Wysocka M., Brzezińska M., Dębowski D., Sieńczyk M., Gorodkiewicz E., Guszcz T., Czaplewski C., Rolka K., Lesner A., Bladder cancer detection using a peptide substrate of the 20S proteasome, FEBS J., 283, 2929-2948 (2016)

3.  Ye X., Guan S., Liu J., Ng C.C., Chan G.H., Sze S.C., Zhang K.Y., Naude R., Rolka K., Wong J.H., Ng T.B., Activities of Venom Proteins and Peptides with Possible Therapeutic Applications from Bees and WASPS, Protein Pept. Lett., 23, 748-755 (2016)

4. Dębowski D., Cichorek M., Lubos M., Wójcik S., Łęgowska A., Rolka K., Noncovalent inhibitors of human 20S and 26S proteasome based on trypsin inhibitor SFTI-1, Biopolymers,  106, 685-696 (2016)

5. Wysocka M., Gruba N., Grzywa R., Giełdoń A., Bąchor R., Brzozowski K., Sieńczyk M., Dieter J., Szewczuk Z., Rolka K., Lesner A., PEGylated substrates of NSP4 protease: A tool to study protease specificity, Sci. Rep., 6, 22856 (2016)

6. Dębowski D., Wyrzykowski D., Lubos M., Rolka K., Interactions between trypsin and its peptidic inhibitors studied by isothermal titration calorimetry (ITC), J. Therm. Anal. Calorim., 123, 807-812 (2016).