2011-2015

Publikacje 2011-2015

2015

1. Gruba N., Wysocka M., Brzezińska M., Debowski D., Rolka K., Martin N., Lesner A., Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome, Anal Biochem. 2015 doi: 10.1016/j.ab.2015.08.019.

2. Karna N., Łęgowska A., Malicki S., Dębowski D., Golik P., Gitlin A., Grudnik P., Wladyka B., Brzozowski K., Dubin G., Rolka K., Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1), Chembiochem., 2015, doi: 10.1002/cbic.201500296.

3. Gitlin A., Dębowski D., Karna N., Łęgowska A., Stirnberg M., Gütschow M., Rolka K., Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1, Chembiochem., 16,1601-1607(2015).

4. Karna N., Dębowski D., Łęgowska A., Bąchor R., Szewczuk Z., Rolka K., Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P1 positions by peptoid monomers, Biopolymers., 104, 206-212 (2015).

5. Brzozowski K., Stawikowski M., Ślusarz R., Sikorska E., Lesner A., Łęgowska A., Rolka K., Conformational Studies of [Nphe5]SFTI-1 by Means of 2D NMR Spectroscopy in
Conjunction with Molecular Dynamics Calculations
, J. Mol. Struct., 1100, 203-207 (2015).

6. Wysocka M., Wojtysiak A., Okońska M., Gruba N., Jarząb M., Wenta T., Lipińska B., Grzywa R., Sieńczyk M., Rolka K., Lesner A., Design and synthesis of new substrates of HtrA2 protease, Anal. Biochem., 15, 44-52 (2015).

7. Grudnik P., Debowski D., Legowska A., Malicki S., Golik P., Karna N., Rolka K., Dubin G., Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin, Proteins., 83, 582-589 (2015).

 

2014

1. Lesner A., Karna N., Łęgowska A., Wysocka M., Guzow K., Sieradzan A., Sieńczyk M., Trzonkowski P., Pikuła P., Zieliński M., Kosikowska P., Łęgowska Ł, Dębowski D., Wiczk W., Rolka K., Fluorescent analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds - synthesis and applicationsBiopolymers, 102, 124-35 (2014).

2. Wysocka M., Gruba N., Miecznikowska A., Popow-Stellmaszyk J., Gütschow M., Stirnberg M., Furtmann, N., Bajorath, J., Lesner A., Rolka K.,  Substrate specificity of human matriptase-2, Biochimie, 97, 121-127 (2014).

3.  Dębowski D., Pikuła M., Lubos M., LangaP., Trzonkowski P., Lesner A., Łęgowska A., Rolka K., Inhibition of human and yeast 20S proteasome by analogues of trypsin inhibitor SFTI-1, POLS One, 2014, accepted

4. Krzywda S., Jaskolski M., Rolka K., Stawikowski S., Structure of a proteolytically resistant analogue of (NLys)5SFTI-1 in complex with trypsin: evidence for the direct participation of the Ser214 carbonyl group in serine protease-mediated proteolysis, Acta Crystallogr. D. Biol. Crystallogr., 70, 668-675 (2014).

2013

1. Debowski D., Łukajtis R., Filipowicz M., Strzelecka P., Wysocka M., Łęgowska, A., Lesner A., Rolka K, Hybrid analogues of SFTI-1 modified in P1 position by β- and γ-amino acids and N-substituted β-alanines, Biopolymers, 100, 154-159 (2013).

2. Walewska A., Han T.S., Zhang M. M., Yoshikami D., Bulaj G., Rolka K., Expanding chemical diversity of conotoxins: peptoid-peptide chimeras of the sodium channel blocker  μ-KIIIA and its selenopeptide analogues, Eur. J. Med. Chem. 65, 144-150 (2013).

3.  Zdzalik  M., Kalinska M., Wysocka M., Stec-Niemczyk J., Cichon P., Stach N., Gruba N., Stennicke H. R., Jabaiah A., Markiewicz M., Kedracka-Krok S., Wladyka B., Daugherty P. S., Lesner A., Rolka K., Dubin A., Potempa J., Dubin G., Biochemical and Structural Characterization of SplD Protease from Staphylococcus ureus, POLS One, 8(10):e76812. (2013).

4.  Karna N., Dębowski D., Gitlin A., Łęgowska A., Rolka K., Investigation of peptide splicing using two-peptide-chain analogs of trypsin inhibitor SFTI-1, FEBS J., 280, 6213-6222 (2013).

5. Popow-Stellmaszyk J, Wysocka M, Lesner A, Korkmaz B, Rolka K., A new proteinase 3 substrate with improved selectivity over human neutrophil elastase, Anal. Biochem., 442, 75-82 (2013).  

6. Wysocka M., Lesner A., Future of protease activity assays. Curr. Pharm. Design., 19, 1062-1067 (2013).  

7. Żurawa-Janicka D., Jarząb M., Polit A., Skórko-Glonek J., Lesner A., Gitlin A., Giełdoń A., Ciarkowski J., Glaza P., Lubomska A., Lipińska B., Temperature-induced changes of HtrA2(Omi) protease activity and structure. Cell Stress  Chaperon.,  18, 35-51 (2013).

8. Debowski D., Natural proteinaceous inhibitors of serine proteases. Curr . Pharm. Des., 19, 1068-1084 (2013).

9. RolkaK. , A. Lesner, A. Łęgowska, M. Wysocka, Peptidic plant origin inhibitors of serine proteinases, [w:] Antitumor Potential and Other Emerging Medicinal Properties of Natural Compounds (E. F. Fang and T. B. Ng, eds.), Springer 2013, ISBN: 978-94-007-6214-5,  str. 187 – 204.

2012

1. Kalińska M., Kantyka T., Greenbaum D.C., Larsen K.S., Władyka B., Jabaiah A., Bogyo M., Daugherty P.S., Wysocka M., Jaros M., Lesner A., Rolka K., Schaschke N., Stennicke H., Dubin A., Potempa J., Dubin G., Substrate specificity of Staphylococcus aureus cysteine proteases - staphopains A, B and C, Biochimie, 94, 318-327 (2012).

2. Dębowski D., Łukajtis .R., Łęgowska A., Karna N., Maliszewska I., Sieńczyk M., Lesner A., Rolka K., Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogues derived from amphibian skin, Peptides, 35, 276-284 (2012).

3. Wysocka M., Lesner A., Korkmaz B., Gauthier F., Kitamatsu M., Gruba N., Rolka K. Three Wavelength Substrate System of Neutrophil Serine Proteinases, Anal. Chem., 84, 7241-7248 (2012).

4. Wysocka M., Lesner A., Popow J., Legowska M., Rolka K., Pegylated Fluorescent Peptides as Substrates of Proteolytic Enzymes, Prot. Peptide Lett., 19, 1237-1244 (2012).

2011

1. Walewska A., Jaśkiewicz A., Bulaj G., Rolka K., Selenopeptide Analogs of EETI-II Retain Potent Trypsin Inhibitory Activities, Chem. Biol. Drug Des., 77, 93-97 (2011)  

2. Łukajtis R., Łęgowska A., Wysocka M., Dębowski D., Lesner a., Rolka K., Analogues of Trypsin Inhibitor SFTI-1 Modified in Conservative P1ʹ Position by Synthetic or Non-Proteinogenic Amino Acids RetainTheir Inhibitory Activiy, J. Pept. Sci., 17, 281-287 (2011).

3. Łęgowska A., Dębowski D., Łukajtis R., Sztabkowska E., Mizeria A., Brzozowski K., Wysocka M., Lesner A., Rolka K., Introduction of Pro and its analogues in the conserved P1’ position of trypsin inhibitor SFTI-1 retains its inhibitory activity, Protein Pept. Lett., 11, 1158-1167 (2011).

4. Wong J. H., Łęgowska A., Rolka K., Ng T.B., Hui M., ChoC.H., Lam W. W. L., Au W. W., Gu O.W., Wan D.C.C., Effects of cathelicidin and its fragments on three key enzymes of HIV-1, Peptides, 32, 1117-22 (2011).

5. Wong J.H,, Ng T.B., Łęgowska A., Rolka K., Hui M., Cho C.H., Antifungal action of human cathelicidin fragment (LL13-37) on Candida albicans, Peptides, 32, 1996-2002 (2011).

6. Lesner A., Łęgowska A., Wysocka M., Rolka K., Sunflower Trypsin Inhibitor 1 as a Molecular Scaffold for Drug Discovery, Curr.Pharm.Design, 17, 4308-4317 (2011).

Pokaż rejestr zmian

Data publikacji: poniedziałek, 13. Styczeń 2014 - 13:16; osoba wprowadzająca: Agata Gitlin Ostatnia zmiana: wtorek, 31. Październik 2017 - 18:11; osoba wprowadzająca: Agata Gitlin