2006-2010 | Wydział Chemii

Publikacje 2006-2010

 

2010

1. Łęgowska A., Bulak E., Jaśkiewicz A, Małuch I., Sieracki M., Wysocka M., Lesner A., Rolka K. Analogues of trypsin inhibitor SFTI-1 with disulfide bridge substituted by various length of carbonyl bridges. Protein and Peptide Letters. - 2010, Vol. 17, no. 10, s. 1223-1227.

2. Wysocka M., Lesner A., Guzow K., Kulczycka J., Łęgowska A., Wiczk W., Rolka K.. Highly specific substrates of proteinase 3 containing 3-(2-Benzoxazol-5-yl)-L-alanine and their application for detection of this enzyme in human serum. Analytical Chemistry. - 2010, Vol. 82, iss. 9, s. 3883-3889.

3. Łęgowska A., Dębowski D., Łukajtis R., Wysocka M., Czaplewski C., Lesner A., Rolka K.. Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases. Bioorganic & Medicinal Chemistry. - 2010, Vol. 18, iss. 23, s. 8188-8193.

4. Łęgowska A., Lesner A., Bulak E., Jaśkiewicz A., Sieradzan A., Cydzik M., Stefanowicz P., Szewczuk Z., Rolka K., Inhibitory activity of double-sequence analogues of trypsin inhibitor SFTI-1 from sunflower seeds : an example of peptide splicing. FEBS Journal. - 2010, Vol. 277, iss. 10, s. 2351-2359.

5. Podstawka-Proniewicz E., Kosior M., Kim Y., Rolka K., Proniewicz L.M., Nociceptin and its natural and specifically-modified fragments : structural studies. Biopolymers. - 2010, Vol. 93, no. 12, s. 1039-1054.

6. Łęgowska A., Dębowski D., Lesner A., Wysocka M., Rolka K., Selection of peptomeric inhibitors of bovine ?-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach. Molecular Diversity. - 2010, Vol. 14, no. 1, s. 51-58.

7. Walewska A., Jaśkiewicz A., Bulaj G., Rolka K., Selenopeptide analogs of EETI-II retain potent trypsin inhibitory activities. Chemical Biology & Drug Design. - 2010, Vol. 77, iss. 1, s. 93-97.

8. Wysocka M., Spichalska B., Lesner A., Jaros M., Brzozowski K., Łęgowska A., Rolka K., Substrate specificity and inhibitory study of human airway trypsin-like protease. Bioorganic & Medicinal Chemistry. - 2010, Vol. 18, iss. 15, s. 5504-5509.

9. Kolaczkowska A., Kolaczkowski M., Sokolowska A., Miecznikowska H., Kubiak A., Rolka K., Polanowski A., The antifungal properties of chicken egg cystatin against Candida yeast isolates showing different levels of azole resistance. Mycotaxon. - 2010, Vol. 53, s. 314-320.

10. Wysocka M., Lesner A., Majkowska G., Łęgowska A., Guzow K., Rolka K., Wiczk W., The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region. Analytical Biochemistry. - 2010, Vol. 399, iss. 2, s. 196-201.
 

2009

1. Lesner A., Wysocka M., Solek M., Łęgowska A., Rolka K., Low-molecular-weight aldehyde inhibitors of cathepsin G.Protein Pept Lett. 16(4),408-410. (2009)

2. Łęgowska A., Dębowski D., Lesner A., Wysocka M., Rolka K., Selection of peptomeric inhibitors of bovine alpha-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach.Mol Divers. 2009 Apr 9 in press

3. Łęgowska A., Dębowski D., Lesner A., Wysocka M., Rolka K., Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors.Bioorg Med Chem. 17(9),3302-3307. (2009)

4. Kolaczkowska A., Kolaczkowski M., Sokolowska A., Miecznikowska H., Kubiak A., Rolka K., Polanowski A., The antifungal properties of chicken egg cystatin against Candida yeast isolates showing different levels of azole resistance.Mycoses. 2009 Jun 22. in press

5. Lesner A., Shilpi R, Ivanova A., Gawinowicz M.A., Lesniak J., Nikolov D., Simm M., Identification of X-DING-CD4, a new member of human DING protein family that is secreted by HIV-1 resistant CD4(+) T cells and has anti-viral activity.Biochem Biophys Res Commun. 389(2),284-289 (2009)

6. Reich M., Lesner A., Łęgowska A., Sieńczyk M., Oleksyszyn J, Boehm B.O., Burster T., Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells.Mol Immunol. 46(15),2994-2999 (2009)

7. Walewska A., Zhang M.M., Skalicky J.J., Yoshikami D., Olivera B.M., Bulaj G., Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins.Angew Chem Int Ed Engl. 48(12),2221-2224 (2009)

8. Han T.S., Zhang M.M., Walewska A., Gruszczynski P., Robertson C.R., Cheatham T.E. 3rd, Yoshikami D., Olivera B.M., Bulaj G., Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics.ChemMedChem. 4(3):406-14. (2009)
 

2008

1. Wysocka M., Lesner A., Rolka K., Influence non proteinogenic phenylalanie analogues in position P1 of the substrate on chymotrypsin specificity, Protein and Peptide Letters 15 (3), 260-264. (2008)

2. Walewska A, Skalicky JJ, Davis DR, Zhang MM, Lopez-Vera E, Watkins M, Han TS, Yoshikami D, Olivera BM, Bulaj G., NMR-Based Mapping of Disulfide Bridges in Cysteine-Rich Peptides: Application to the mu-Conotoxin SxIIIA , J Am Chem Soc., 130 (43), 14280-14286. (2008)

3. Sieńczyk M., Lesner A., Wysocka M., Łegowska A., Pietrusewicz E., Rolka K., Oleksyszyn, J. New potent cathepsin G phosphonate inhibitors, (2008) Bioorganic and Medicinal Chemistry

4. Lopez-Vera E., Walewska A., Skalicky J.J., Olivera B.M., Bulaj G. Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins Biochemistry, 47 (6), pp. 1741-1751. (2008)

5. Spichalska B. Lesner A., Wysocka M., Śledź M., Łęgowska A., Jaśkiewicz A., Miecznikowska H., Rolka K., The influence of substrate peptide length on human ?-tryptase specificity, Journal of Peptide Science, 14 (8), pp. 917-923. (2008)

6. Brzozowski K., Majewski R., Jaśkiewicz A., Łęgowska A., Klaudel L., Rodziewicz-Motowidło, S., Rolka, K., Conformational studies of (Abu3,11)-SFTI- 1, an analogue of the trypsin inhibitor isolated from sunflower seeds, Journal of Peptide Science, 14 (8), pp. 911-916. (2008)

7. Wysocka M., Lesner A., Guzow K., Mackiewicz L., Łęgowska A., Wiczk W., Rolka K., Design of selective substrates of proteinase 3 using combinatorial chemistry methods Analytical Biochemistry, 378 (2), pp. 208-215. (2008)

8. Łęgowska A., Bulak E., Wysocka M., Jaśkiewicz A., Lesner A., Dębowski D., Rolka, K., Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds Bioorganic and Medicinal Chemistry, 16 (10), pp. 5644-5652. (2008)

9. Lesner A., Wysocka M., Guzow K., Wiczk W., Łęgowska A., Rolka K., Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods Analytical Biochemistry, 375 (2), pp. 306-312. (2008)

10. Wysocka M., Lesner A., Łęgowska A., Jaśkiewicz A., Miecznikowska H., Rolka K. Designing of substrates and inhibitors of bovine alpha-chymotrypsin with synthetic phenylalanine analogues in position P(1). Protein Pept Lett. 15(3),260-264. (2008)
 

2007

1. Berti F, Gaggelli E, Guerrini R, Janicka A, Kozlowski H, Legowska A, Miecznikowska H, Migliorini C, Pogni R, Remelli M, Rolka K, Valensin D, Valensin G. Structural and dynamic characterization of copper(II) binding of the human prion protein outside the octarepeat region, Chemistry. 13, 1991(2007).

2. Li G., Li Y., Kazmierczak K., Lesner A., Aaron S., Bentsman G., Potash M. J., Simm M., An anti-NF-?B activity of HRF, a soluble factor secreted by an HIV-1 resistant cell line, blocks inflammatory responses in human macrophages after their exposure to HIV-1 and various bacterial LPS antigens, Immunol Cell Biol. 2007 in pres.

3. Wysocka M., Kwiatkowska B., Rzadkiewicz M., Lesner A. Rolka K., Selection of new chromogenic substrates of serine proteinases using combinatorial chemistry methods, Comb. Chem. High Troug, S. 3, 171-180(2007).

4. Wysocka M.,Łęgowska A., Bulak E., Jaśkiewicz A., Miecznikowska H., Lesner A., Rolka K. New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P1 selected by combinatorial chemistry methods, Mol Divers. 11, 93-99(2007).

5. Kowalska J., Pszczoła K., Wilimowska-Pelc A., Lorenc-Kubis I., Zuziak E., Ługowski M., Łęgowska A., Kwiatkowska A., Śleszyńska M., Lesner A., Walewska A., Zabłotna E., Rolka K., Wilusz T., Trypsin inhibitors from garden four-o'clock and spinach: isolation, characterization and chemical synthesis, Phytochemistry. 68, 1487(2007).

6. Zabłotna E, Jaśkiewicz A, Lęgowska A, Miecznikowska H, Lesner A, Rolka K. Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI-1 as a starting structure, J Pept Sci. 13, 749-755(2007).

7. Li, G., Aaron, S., Kazmierczak, K., Lesner, A., Li, Y., Ivanova, A., Bentsman, G., Potash, M.J., Simm, M. Inhibition of HIV-1 or bacterial activation of macrophages by products of HIV-1-resistant human cells , Immunology and Cell Biology, 85 (8),603-609.(2007)
 

2006

1. Suder P, Bierczynska-Krzysik A, Kraj A, Brostedt P, Mak P, Stawikowski M, Rolka K, Nyberg F, Fries E, Silberring J. Identification of bikunin as an endogenous inhibitor of dynorphin convertase in human cerebrospinal fluid, FEBS J. 273, 5113-5120(2006).

2. Zabłotna E, Kret A, Jaśkiewicz A, Olma A, Leplawy MT, Rolka K. Introduction of alpha-hydroxymethyamino acid residues in substrate specificity P1 position of trypsin inhibitor SFTI-1 from sunflower seeds retains its activity, Biochem Biophys Res Commun. 340, 823-828(2006).

Treść ostatnio zmodyfikowana przez: Agata Gitlin
Treść wprowadzona przez: Agata Gitlin
Ostatnia modyfikacja: 
poniedziałek, 13 stycznia 2014 roku, 11:02